EGTA螯合CaB+ 将会干扰以CaB+ 作为第二信使的信号传导途径。肝细胞中胰高血糖素诱导的糖原分解要经由cAMP途径, 因此不会影响EGTA的作用。
问答题What functional roles do the ECM (细胞外基质)and cell wall share in common
判断题Atrial natriuretic peptides(心钠肽) bind to a receptor that activates a G protein,which in turn activates guanylyl cyclase(鸟苷环化酶) to produce cyclic GMP which then activates a cyclic GMP-dependent protein kinase (PKG).
判断题It is thought that extracellular ligand binding to a receptor tyrosine kinase activates the intracellular catalytic domain by propagating a conformational change across the lipid bilayer through the single transmembrane a helix.
判断题Protein kinase A itself is different in different cell types, whichexplains why the effects of cyclic AMP vary depending on the target cell.
判断题How is it that different cells can respond in different ways to exactly the same signaling molecule even when they have identical receptors